There is limited knowledge of the impacts of honey bee hives on wild bees and the amount of floral resources honey bees require, which are both needed for addressing whether landscapes have enough resources for all bees. ...

Pyridines are important frameworks in drug development, valued for their ubiquitous presence in biologically active compounds. As such, we have taken a keen interest in developing mild methods for pyridylic functionalization ...

Pannexin1 (Panx1) forms ATP-permeable single membrane channels that play a role in the (patho)physiology of the nervous system. Two independent copies of panx1 (i.e., panx1a and panx1b) have been identified in the zebrafish. ...

Deserts are ecologically important ecosystems that contain high levels of endemism and that are sensitive to global change. Positive interactions among plants have been cited as factors that support desert biodiversity by ...

Bees provide crucial pollination services to both cultivated and wild plants. In recent decades there were large declines in the populations of several native bee species and in the health of managed honey bee colonies. ...

Digestive enzymes are essential for the catabolism of macromolecules and are produced endogenously by the animal or exogenously by the gastrointestinal bacteria. This thesis explored the contribution of endogenous versus ...

The oxidative stress response protects the cell by balancing the number of free radicals inside the cell. BRAP2 is a Ras effector with ubiquitin ligase activity and conserved in C. elegans. Our lab has previously shown ...

Many northern fishes are experiencing unprecedented environmental changes across their ranges. However, limited empirical evidence exists for understanding how these changes may combine and potentially interact to influence ...

The synergic actions of calcium, calmodulin, and calmodulin kinase II are the central mechanism for synaptic plasticity. Until the last two decades, chemical synapses through N-methyl D-aspartate receptors were thought to ...

Seizures are a hallmark of epilepsy and are associated with many other diseases. However, their molecular determinants are not well understood. A membrane glycoprotein, Pannexin1, has been implicated in seizures for its ...