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Understanding honey bee forage requirements and the impacts of urban hives on wild bees
(2021-07-06)
There is limited knowledge of the impacts of honey bee hives on wild bees and the amount of floral resources honey bees require, which are both needed for addressing whether landscapes have enough resources for all bees. ...
Palladium-Catalyzed Functionalization of 4-Alkylpyridines: Pyridlyic Dehydrogenation & Mechanistic Investigation of Pyridylic Allylation
(2021-03-08)
Pyridines are important frameworks in drug development, valued for their ubiquitous presence in biologically active compounds. As such, we have taken a keen interest in developing mild methods for pyridylic functionalization ...
Roles of Panx1 Channels in Larval Zebrafish: From Genes to Visual-Motor Behavior
(2021-07-06)
Pannexin1 (Panx1) forms ATP-permeable single membrane channels that play a role in the (patho)physiology of the nervous system. Two independent copies of panx1 (i.e., panx1a and panx1b) have been identified in the zebrafish. ...
Examining Mechanisms of Positive Plant Interactions in Deserts
(2021-07-06)
Deserts are ecologically important ecosystems that contain high levels of endemism and that are sensitive to global change. Positive interactions among plants have been cited as factors that support desert biodiversity by ...
What's Really Out There? Investigations into the Effects of Pesticides and Pathogens on Bee Health
(2021-03-08)
Bees provide crucial pollination services to both cultivated and wild plants. In recent decades there were large declines in the populations of several native bee species and in the health of managed honey bee colonies. ...
Enzyme Activities in the Intestinal Layers of Teleost Fishes: Endogenous versus Exogenous Contribution
(2021-03-08)
Digestive enzymes are essential for the catabolism of macromolecules and are produced endogenously by the animal or exogenously by the gastrointestinal bacteria. This thesis explored the contribution of endogenous versus ...
The Role Of Vab-3 in the Caenorhabditis Elegans Oxidative Stress Response
(2021-03-08)
The oxidative stress response protects the cell by balancing the number of free radicals inside the cell. BRAP2 is a Ras effector with ubiquitin ligase activity and conserved in C. elegans. Our lab has previously shown ...
Understanding How Northern North American Freshwater Fishes are Responding to Rapid Environmental Change
(2021-03-08)
Many northern fishes are experiencing unprecedented environmental changes across their ranges. However, limited empirical evidence exists for understanding how these changes may combine and potentially interact to influence ...
Roles of Calmodulin and a N-Methyl-D-Aspartate Receptor - Pannexin-1 Signaling Complex in Connexin-36 Plasticity
(2021-03-08)
The synergic actions of calcium, calmodulin, and calmodulin kinase II are the central mechanism for synaptic plasticity. Until the last two decades, chemical synapses through N-methyl D-aspartate receptors were thought to ...
The Zebrafish Pannexin1a and Pannexin1b Ohnologs Contribute Differentially to Seizure Propagation In Vivo
(2021-11-15)
Seizures are a hallmark of epilepsy and are associated with many other diseases. However, their molecular determinants are not well understood. A membrane glycoprotein, Pannexin1, has been implicated in seizures for its ...