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Novel Kinetic Solution-Based Separation Approaches for Small Molecule Drug Discovery 

Bao, Jiayin (2017-07-27)
The modern pharmaceutical industry has achieved remarkable successes in medicinal chemistry. However, many diseases are incurable due to the difficulty of finding new drugs. De novo drug discovery contains two steps: the ...
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Characterization of Structures and Dynamics of Intrinsically Disordered Domain and Proteins Using Time Resolved-Hydrogen Deuterium Exchange Mass Spectrometry 

Zhu, Shaolong (2017-07-27)
Proteins are inherently dynamic. Virtually all of the processes that underlie biological activity, including binding partner recognition, catalysis and allostery among many others, require transient adoption of specific ...
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Chemical and Physical Studies of Secondary Organic Aerosol Formed from Beta-pinene Photooxidation 

Sarrafzadeh, Mehrnaz (2017-07-27)
Atmospheric organic aerosols have a significant impact on climate and human health. However, our understanding of the physical and chemical properties of these aerosols is inadequate, thus their climate and health influences ...
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Structure-Function Studies of Scaffolding Proteins Involved in the Formation of Neuronal Connections: AIDA1 and CASKIN2 

Smirnova, Ekaterina (2017-07-27)
Modular proteins serve assembly platforms and often actively regulate cellular signaling events. An intrinsic diversity of interaction modules, typical for scaffolding proteins, facilitates the organization of numerous ...
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Synthesis of Primary Arylamines Using Bulky Palladium N-heterocyclic Carbene Precatalysts 

Lombardi, Christopher Daniel (2017-07-27)
The reaction between aryl halides and ammonia was investigated using N-heterocyclic carbene (NHC) ligated palladium pre-catalysts. The use of NHCs is well documented for coupling of alkyl and arylamines, but there is little ...
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Structural and Functional Studies of TraG From the F Plasmid and the Major Pilin From Coxiella Burnetii 

Erdogan, Fettah (2017-07-26)
The Escherichia coli F-plasmid houses all genes necessary for the assembly of its conjugative machinery to facilitate successful DNA transfer. TraG is one of the largest proteins (102 kDa) encoded in the transfer (tra) ...

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AuthorBao, Jiayin (1)Erdogan, Fettah (1)Lombardi, Christopher Daniel (1)Sarrafzadeh, Mehrnaz (1)Smirnova, Ekaterina (1)Zhu, Shaolong (1)SubjectChemistry (3)Mass spectrometry (3)Alzheimer's disease (1)Amination (1)Aminotriphenysilane (1)Ammonia (1)Amyloid (1)Amyloid-beta precursor protein (1)Analytical chemistry (1)Anti-aggregation (1)... View MoreDate Issued
2017 (6)
Has File(s)
Yes (6)

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.

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