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The Effects of Prior Knowledge on Mnemonic Discrimination in Young and Other Adults, and in Hippocampal Amnesia

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dc.contributor.advisor Rosenbaum, Shayna
dc.creator Pishdadian, Sara
dc.date.accessioned 2018-11-21T13:53:31Z
dc.date.available 2018-11-21T13:53:31Z
dc.date.copyright 2018-08-01
dc.date.issued 2018-11-21
dc.identifier.uri http://hdl.handle.net/10315/35565
dc.description.abstract The hippocampus is critical to discriminating between newly learned, highly similar stimuli; less clear is its role in discriminating representations based on prior knowledge. In this study, young adults, older adults divided by performance on a cognitive screening measure, and people with hippocampal amnesia were asked to discriminate between pairs of real-world familiar landmarks and well-known animals using the metrics of geographical distance and size. Results showed all participants had lower accuracy for judgments with more similar item pairs. Low-performing older adults showed selectively worse performance on judgments with more similar item pairs. Amnesic individuals performance appeared to depend on lesion location. Only patient BL, who has selective bilateral dentate gyrus lesions, had difficulty on the landmark task when judging between highly similar distances. These results reinforce the importance of investigating representation similarity, even for well-established representations, and offer insight into mnemonic discrimination across the lifespan and within amnesia.
dc.language.iso en
dc.rights Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subject Neurosciences
dc.title The Effects of Prior Knowledge on Mnemonic Discrimination in Young and Other Adults, and in Hippocampal Amnesia
dc.type Electronic Thesis or Dissertation
dc.degree.discipline Psychology(Functional Area: Clinical Psychology)
dc.degree.name MA - Master of Arts
dc.degree.level Master's
dc.date.updated 2018-11-21T13:53:31Z
dc.subject.keywords Memory
dc.subject.keywords Episodic memory
dc.subject.keywords Spatial memory
dc.subject.keywords Pattern separation
dc.subject.keywords Mnemonic discrimination
dc.subject.keywords Hippocampus
dc.subject.keywords Aging
dc.subject.keywords Older adults
dc.subject.keywords Amnesia
dc.subject.keywords Hippocampal amnesia
dc.subject.keywords Memory loss
dc.subject.keywords Semantic
dc.subject.keywords Semantic memory
dc.subject.keywords Prior knowledge
dc.subject.keywords Dentate gyrus
dc.subject.keywords Lesion
dc.subject.keywords Neuropsychology

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