Biology
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Effects of Climate Change on Lake Ice Freeze Up Across the Northern Hemisphere: Historical Patterns and Future Predictions
(2019-07-02)Shifts in freeze up dates signal climatic change. We examined nine lakes in the Great Lakes region to forecast freeze up dates into the future. We also examined 75 lakes around the Northern Hemisphere to understand how and ... -
The Role of a -Catenin - FMRP Complex In Skeletal Muscle
(2019-07-02)Skeletal muscle consists of multinucleated myofibers which generate contractile force and regulate glucose levels in the human body. Over time, skeletal muscle can become damaged and therefore requires a robust capacity ... -
Investigating Changes in Lake Ice Breakup Under Current and Future Climate Change
(2019-07-02)Changes in climate profoundly influence the timing of lake ice breakup. We assessed: 1) potential future changes in lake ice breakup date in the Great Lakes Region and 2) historical linear changes and shifts in ice breakup ... -
Measuring the exposure of Songbird Nestlings to Neonicotinoids in Natural and Agricultural Nest Sites
(2019-07-02)Neonicotinoid insecticides such as imidacloprid (IMI) have been under scrutiny for their damage on non-target invertebrates. However, recent literature suggests that grassland birds are experiencing population declines ... -
Investigating Interaction Partners Of Yeast UBPS and Human USP7 Deubiquitinases
(2019-07-02)Ubiquitin-specific proteases (USPs; Ubps) are the most abundant family of deubiquitinating enzymes. Their involvement in various cellular processes, which are implicated in development and diseases such as cancer, have ... -
Investigating the Effects of Sumoylation on the Yeast General Transcription Factor TFIIF
(2019-03-05)Sumoylation is a post-translational modification that regulates numerous cellular processes including gene expression. We find that among the general transcription factors of RNA Polymerase II (RNAPII) in budding yeast, ... -
The Role of miR-590-3p in Regulating Human Epithelial Ovarian Cancer Development
(2019-03-05)Epithelial ovarian cancer (EOC) has the highest mortality rate among all gynecological malignancies. Early detection and intervention remain key to patient prognosis fueling the search for reliable biomarkers. MicroRNAs ... -
Pollinator-Mediated Interactions of Foundation Plants in the Mojave Desert
(2019-03-05)Pollination facilitation is an indirect interaction whereby one plant species positively influences the reproductive success of another plant species through pollinators. First, we conducted a systematic review of the ... -
Elucidating the Mechanisms Surrounding H2A.X Monoubiquitylation Marks in the DNA Damage Response Pathway
(2019-03-05)In response to DNA double-strand breaks (DSBs), H2A.X undergoes three post-translational modifications (PTMs) reported to be important for DSB signaling: phosphorylation at serine 139, monoubiquitylation at lysines 118/119 ... -
Searching for the Genetic Basis of Hygienic Behavior and Overwintering in the Honeybee (Apis mellifera)
(2019-03-05)The recent decline in honeybee populations can be mitigated through genomics and marker-assisted selection. The current techniques, such as chemical treatment to prevent disease, are only short-term solutions. The ability ... -
Uncovering Markers for Honey Production and Defensive Behaviour Using Pooled Genome-Wide Data with the Honeybee (Apis Mellifera)
(2019-03-05)The honeybee (Apis mellifera) has been an important insect for both the study of social insect behaviour and agriculture. Honey production and defensive behaviour are honeybees two notable and economically valuable traits. ... -
Investigating Gastrointestinal Tract Functional Zonation in the Gut Microbiome and Enzyme Activity of Oncorhynchus mykiss (Rainbow Trout) with Temperature and Ion-poor Water Salinity Challenge
(2019-03-05)The regional distribution of digestion, metabolic, osmoregulatory and detoxification function along the GIT of fish are poorly understood. Several studies have shown evidence for zonation in the enzyme activity and zonation ... -
Tagging Endogenous H2A.Z1 and H2A.Z2 Histone Variant Isoforms Using CRISPR-Cas9 and Identifying SUMOylated Proteins in Proximity to H2A.Z-Containing Nucleosomes
(2018-11-21)H2A.Z is a variant of the H2A core histone, and is well known to be important for transcriptional regulation in eukaryotic cells. It was recently discovered that higher eukaryotes have two almost identical isoforms of H2A.Z ... -
GCD10 and GCD14 Proteins Facilitate Tomato Bushy Stunt Viral (TBSV) RNA Replication in Saccharomyces Cerevisiae
(2018-11-21)Tomato bushy stunt virus (TBSV) is a positive-sense RNA virus and its genome replication requires two viral proteins, p33 and RNA-dependent RNA polymerase p92. Previous studies showed that the 5 untranslated region (5UTR) ... -
Biosystematics of the Cleptoparasitic Bee Genus Epeolus Latreille and its Ecological and Evolutionary Relationship with Its Hosts of the Bee Genus Colletes Latreille
(2018-11-21)Cleptoparasitic (cuckoo) bees are those that appropriate food stores from bees in other genera for their own offspring. Upwards of 15% of all bees and 28% of the family Apidae are cleptoparasitic. Despite their taxonomic ... -
The Role of MicroRNA-378a-5p and its Target Genes in Differentiation and Fusion of BeWo Cells
(2018-11-21)MicroRNAs are the post-transcriptional modulators of gene expression and have been shown to play vital roles in the placental development. The placenta is a multifunctional organ that plays critical roles throughout the ... -
Characterization of the Adipokinetic Hormone/Corazonin-Related Peptide Signalling System in the Mosquito, Aedes Aegypti
(2018-11-21)The adipokinetic hormone/corazonin-related peptide (ACP) is an insect neuropeptide structurally intermediate between corazonin (CRZ) and adipokinetic (AKH) hormones, which all demonstrate homology to the vertebrate ... -
Human La Function in Expression of Coding Transcripts
(2018-11-21)The La protein, also referred to as Sjogrens Syndrome antigen B (SSB), is an RNA-binding phosphoprotein first identified as an auto-antigen in patients suffering from Sjogrens syndrome and systemic lupus erythematosus. La ... -
Distribution of Ionomotive Pumps and Control of Malpighian Tubule Secretion By Cyclic Nucleotides in the Black-Legged Tick, Ixodes Scapularis
(2018-11-21)Ticks have a hematophagous feeding strategy, and thus must regulate the uptake of excess ions and fluids during blood meal engorgement through ion and osmoregulation. The salivary glands are essential for tick hydromineral ... -
Regulation and Function of MEF2 in Cardiomyocytes
(2018-11-21)Regular formation of the mammalian heart needs precise spatial and temporal transcriptional regulation of gene programs in ardiomyocytes. Cardiac transcription factors are defined, in this context, as essential transcriptional ...
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