Manufacturing, Characterization and Modeling of Helical Electrospun Fibers for Cardiac Tissue Engineering

Simple item page
dc.contributor.advisorCzekanski, Alex
dc.contributor.authorAlAttar, Ahmed Ali Atif
dc.date.accessioned2023-03-28T21:12:10Z
dc.date.available2023-03-28T21:12:10Z
dc.date.copyright2021-10-08
dc.date.issued2023-03-28
dc.date.updated2023-03-28T21:12:10Z
dc.degree.disciplineMechanical Engineering
dc.degree.levelMaster's
dc.degree.nameMASc - Master of Applied Science
dc.description.abstractCardiovascular disease is a predicament that affects the entire world. Complications arise due to inadequate blood supplied to the heart muscle, which leads to scar tissue formation and ventricular dilation. One of the proven methods to promote cellular regeneration is the implantation of seeded scaffolds using stem cell therapy. Electrospinning has been selected to manufacture scaffolds due to the providing a suitable structure to promote cultivation of cells. Each application requires a set of criteria to be met in a seeded scaffold. In cardiac applications, the mechanical properties and matrix structure need to align with the native tissue. In this thesis, the optimal process parameters to attain electrospun helical fibers are determined. Secondly, the material behaviors of helical scaffolds are examined under different loading schemes. Lastly, numerical modeling for the experimental data is evaluated.
dc.identifier.urihttp://hdl.handle.net/10315/40948
dc.languageen
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subjectMechanical engineering
dc.subjectBiomedical engineering
dc.subjectEngineering
dc.subject.keywordsScaffolds
dc.subject.keywordsCardiac
dc.subject.keywordsElectrospining
dc.subject.keywordsHelical
dc.subject.keywordsMechanical properties
dc.subject.keywordsNumerical modeling
dc.subject.keywordsProcess parameters
dc.subject.keywordsMaterial behavior
dc.subject.keywordsCardiovascular disease
dc.subject.keywordsCVD
dc.titleManufacturing, Characterization and Modeling of Helical Electrospun Fibers for Cardiac Tissue Engineering
dc.typeElectronic Thesis or Dissertation

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
AlAttar_Ahmed_A_2021_Masters.pdf
Size:
4.89 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
license.txt
Size:
1.87 KB
Format:
Plain Text
Description:
Download
No Thumbnail Available
Name:
YorkU_ETDlicense.txt
Size:
3.39 KB
Format:
Plain Text
Description:
Download

Collections

Mechanical Engineering

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.