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dc.contributor.authorGrace, Sherry
dc.contributor.authorBritto, Rachel R.
dc.contributor.authorOh, Paul
dc.contributor.authorRibeiro, Antonio L.
dc.contributor.authorChaves, Gabriela
dc.contributor.authorLima de Melo Ghisi, Gabriela
dc.date.accessioned2021-05-10T17:21:35Z
dc.date.available2021-05-10T17:21:35Z
dc.date.issued2020-11
dc.identifier.citationJournal of Cardiopulmonary Rehabilitation and Prevention, Volume 40, Number 6, November 2020, pp. 399-406(8).en_US
dc.identifier.issn1932-7501
dc.identifier.urihttps://doi.org/10.1097/HCR.0000000000000512en_US
dc.identifier.urihttp://hdl.handle.net/10315/38314
dc.description.abstractPurpose: The impact of comprehensive cardiac rehabilitation (CCR) in Latin America is not well known. Herein, the pre-specified tertiary outcomes of a cardiac rehabilitation (CR) trial are reported: disease-related knowledge, depressive symptoms, and heart-health behaviors (exercise, diet, and smoking). Methods: This was a single-blinded, single-center (Brazil) randomized trial with three parallel arms: CCR (exercise + education) versus exercise-only CR versus wait-list control. Eligible patients were randomized in blocks of four with 1:1:1 concealed allocation. The CR program was 6 mo long. Participants randomized to exercise-only CR received 36 exercise classes; the CCR group also received 24 educational sessions, including a workbook. All outcomes were assessed at pre-test and 6-mo later (blinded). Analysis of covariance was performed by intention-to-treat (ITT) and per-protocol (PP). Results: A total of 115 (89%) patients were randomized; 93 (81%) were retained. There were significant improvements in knowledge with CCR (ITT [51.2 ± 11.9 pre and 60.8 ± 13.2 post] and PP; P < .01), with significantly greater knowledge with CCR versus control (ITT mean difference [MD] = 9.5, 95% CI, 2.3-16.8) and CCR vs exercise-only CR at post-test (ITT MD = 6.8, 95% CI, 0.3-14.0). There were also significant improvements in self-reported exercise with CCR (ITT [13.7 ± 15.8 pre and 32.1 ± 2 5.7 post] and PP; P < .001), with significantly greater exercise with CCR versus control at post-test (ITT MD = 7.6, 95% CI, 3.8-11.4). Also, there were significant improvements in diet with CCR (PP: 3.4 ± 7.5 pre and 8.0 ± 7.0 post; P < .05). Conclusions: In this first-ever randomized trial of CR for coronary artery disease in Latin America, the benefits of CCR have been supported.en_US
dc.language.isoenen_US
dc.publisherWolters Kluweren_US
dc.rightsThis is a non-final version of an article published in final form in (Journal of Cardiopulmonary Rehabilitation and Prevention, Volume 40, Number 6, November 2020, pp. 399-406(8). https://cdn-tp2.mozu.com/16833-m1/cms/files/AuthorDocument.pdf?_mzts=636519775710000000en_US
dc.rights*
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dc.subjectcoronary artery diseaseen_US
dc.subjectcardiac rehabilitationen_US
dc.subjectpatient educationen_US
dc.subjectrandomized controlled trialsen_US
dc.titleComprehensive Cardiac Rehabilitation Effectiveness in a Middle-Income Setting : A Randomized Controlled Trialen_US
dc.typeArticleen_US
dc.rights.journalhttps://www.ingentaconnect.com/content/wk/hcr;jsessionid=69rfc6dlj0brk.x-ic-live-01en_US
dc.rights.publisherhttps://www.wolterskluwer.com/en-caen_US
dc.rights.articlehttps://www.ingentaconnect.com/content/wk/hcr/2020/00000040/00000006/art00011en_US


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