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Sex Differences in the Influence of Brain and Lifestyle Factors on Neurocognitive Aging

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dc.contributor.advisor Turner, Gary
dc.creator Van Den Brink, Christina Joanne
dc.date.accessioned 2016-11-25T14:16:55Z
dc.date.available 2016-11-25T14:16:55Z
dc.date.copyright 2016-08-16
dc.date.issued 2016-11-25
dc.identifier.uri http://hdl.handle.net/10315/32774
dc.description.abstract Declines in executive functioning (EF) are a hallmark of neurocognitive aging. Much research has focused on the impact of exercise, brain structure, and brain function on neurocognitive aging, yet their relative predictive weights had not been evaluated. Further, the impact of sex differences on the influence of these factors had not yet been investigated. Fifty-one older adults participated in this study evaluating the outcome of cardiorespiratory fitness (CRF), prefrontal cortex volume, and global efficiency of functional brain networks on EF. A stratified, multiple hierarchical regression was performed to identify the best predictors of EF for each sex. For females, a model containing solely CRF served as the best predictor of EF. A model containing both CRF and network efficiency best predicted EF in males. These results demonstrate that CRF and metrics of structural and functional brain health in older adulthood are independently associated with EF in a sex-dependent manner.
dc.language.iso en
dc.rights Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subject Neurosciences
dc.title Sex Differences in the Influence of Brain and Lifestyle Factors on Neurocognitive Aging
dc.type Electronic Thesis or Dissertation
dc.degree.discipline Psychology (Functional Area: Clinical Psychology)
dc.degree.name MA - Master of Arts
dc.degree.level Master's
dc.date.updated 2016-11-25T14:16:55Z
dc.subject.keywords Executive functions
dc.subject.keywords Neurocognitive aging
dc.subject.keywords Cardiorespiratory fitness
dc.subject.keywords Global efficiency
dc.subject.keywords Default network
dc.subject.keywords Sex differences

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