Assessment of a Cognitive-Motor Training Program in Adults at Increased Risk for Developing Dementia

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dc.contributor.advisorSergio, Lauren E.
dc.creatorEchlin, Holly
dc.date.accessioned2018-11-21T13:47:39Z
dc.date.available2018-11-21T13:47:39Z
dc.date.copyright2018-07-30
dc.date.issued2018-11-21
dc.date.updated2018-11-21T13:47:39Z
dc.degree.disciplineKinesiology & Health Science
dc.degree.levelMaster's
dc.degree.nameMSc - Master of Science
dc.description.abstractWith the prevalence of dementia increasing each year, preclinically implemented therapeutic interventions are critically needed. It has been suggested that cascading neural network failures may bring on behavioural deficits associated with Alzheimers disease. Previously we have shown that cognitive-motor integration (CMI) training in adults with mild cognitive impairments generalized to improved global cognitive and activities of daily living scores. Here we employ a novel movement-control based training approach involving CMI rather than traditional cognition-only brain training. We hypothesized that such training would stimulate widespread neural networks and enhance rule-based visuomotor ability in at-risk individuals. We observed a significant improvement in bimanual coordination in the at-risk training group. We also observed significant decreases in movement variability for the most complex CMI condition in the at-risk and healthy training groups. These data suggest that integrating cognition into action in a training intervention may be effective at strengthening vulnerable brain networks in asymptomatic adults at risk for developing dementia.
dc.identifier.urihttp://hdl.handle.net/10315/35528
dc.language.isoen
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subjectHealth sciences
dc.subject.keywordsPreclinical
dc.subject.keywordsDementia
dc.subject.keywordsAlzheimer's disease
dc.subject.keywordsCognitive-motor integration
dc.subject.keywordsThinking-while-moving
dc.subject.keywordsBimanual coordination
dc.subject.keywordsMotor control
dc.subject.keywordsAging
dc.subject.keywordsAgeing
dc.subject.keywordsAt-risk
dc.subject.keywordsFrontoparietal
dc.subject.keywordsVideo-games
dc.subject.keywordsNetwork failure
dc.subject.keywordsVisuomotor
dc.subject.keywordsBrain dysfunction indicator
dc.subject.keywordsBrDI
dc.subject.keywordsNeurodegeneration
dc.titleAssessment of a Cognitive-Motor Training Program in Adults at Increased Risk for Developing Dementia
dc.typeElectronic Thesis or Dissertation

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