Effects of Exposure to CdSe/ZnS Quantum Dots on the Neurophysiological Performance of Developing Zebrafish

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dc.contributor.advisorKwong, Raymond
dc.contributor.authorZonouzi-Marand, Mahtab
dc.date.accessioned2020-08-11T12:51:54Z
dc.date.available2020-08-11T12:51:54Z
dc.date.copyright2020-04
dc.date.issued2020-08-11
dc.date.updated2020-08-11T12:51:54Z
dc.degree.disciplineBiology
dc.degree.levelMaster's
dc.degree.nameMSc - Master of Science
dc.description.abstractThis research investigated the effects of exposure to sublethal concentrations of CdSe/ZnS quantum dots on the neurophysiological performance of larval zebrafish. Whole body metal content, physiological conditions, and neurobehavioural responses were examined. The results suggested that exposure to QDs for 5 days increased whole body content of cadmium (Cd). QDs exposure did not affect survival rate, gross morphology, hatching rate, and body length of larvae. However, larvae exposed to QDs exhibited a significant reduction in locomotor activities. Larval anxiety-like behaviours were examined via thigmotaxis and light/dark preference behaviours and the results suggested inhibition of thigmotactic behaviours only in larvae exposed to low concentrations and attenuation of normal dark-avoidance behaviours in the exposed larvae.
dc.identifier.urihttp://hdl.handle.net/10315/37767
dc.languageen
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subjectNanoscience
dc.subject.keywordsToxicity
dc.subject.keywordsNeurotoxicity
dc.subject.keywordsZebrafish
dc.subject.keywordsNanoparticle
dc.subject.keywordsNanomaterial
dc.subject.keywordsNanoparticles
dc.subject.keywordsNanomaterials
dc.subject.keywordsENM
dc.subject.keywordsNP
dc.subject.keywordsEngineered nanomaterials
dc.subject.keywordsLarvae
dc.subject.keywordsLarva
dc.subject.keywordsNeurophysiological
dc.subject.keywordsNeurobehavioural
dc.subject.keywordsNeurobehaviour
dc.subject.keywordsBehaviour
dc.subject.keywordsPerformance
dc.subject.keywordsLocomotion
dc.subject.keywordsThigmotaxis
dc.subject.keywordsLight/dark preference
dc.subject.keywordsVelocity
dc.subject.keywordsWall-hugging
dc.subject.keywordsQuantum dot
dc.subject.keywordsQuantum dots
dc.subject.keywordsQD
dc.subject.keywordsQDs
dc.subject.keywordsCadmium
dc.subject.keywordsSelenium
dc.subject.keywordsCdSe/ZnS
dc.subject.keywordsCadmium selenide
dc.subject.keywordsMetal
dc.titleEffects of Exposure to CdSe/ZnS Quantum Dots on the Neurophysiological Performance of Developing Zebrafish
dc.typeElectronic Thesis or Dissertation

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