The Effect of Upright Posture on Endothelial Function in Women and Men

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dc.contributor.advisorEdgell, Heather
dc.contributor.authorHabib, Karim Hany
dc.date.accessioned2021-11-15T15:35:27Z
dc.date.available2021-11-15T15:35:27Z
dc.date.copyright2021-08
dc.date.issued2021-11-15
dc.date.updated2021-11-15T15:35:27Z
dc.degree.disciplineKinesiology & Health Science
dc.degree.levelMaster's
dc.degree.nameMSc - Master of Science
dc.description.abstractWe investigated flow-mediated dilation (FMD) and reactive hyperemia peripheral arterial tonometry (RH-PAT) responses during the supine and 70 head-up tilt postures to assess vascular function in young healthy women and men. During the FMD protocol: 1) FMD increased in both sexes during tilt (P=0.005), 2) women had higher shear stress responses in both postures vs. men (P=0.03), 3) at the time of maximal vasodilation during tilt, both sexes had lower mean arterial pressure responses (MAP; P=0.02) compared to supine. During the RH-PAT protocol: 1) at all timepoints men had greater RH-PAT in comparison to women (P=0.035), 2) both sexes had similar arterial stiffness in both postures (P>0.05), and 3) at the time of maximal vasodilation, both sexes showed similar MAP responses across both postures (P>0.05). We suggest that the increased vasodilatory response as measured by FMD in the tilt posture could be attributed to increasing metabolite production from postural muscles.
dc.identifier.urihttp://hdl.handle.net/10315/38746
dc.languageen
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subjectKinesiology
dc.subject.keywordsFlow-mediated dilation
dc.subject.keywordsperipheral arterial tonometry
dc.subject.keywordssex differences
dc.subject.keywordsvasodilation
dc.subject.keywordsupright posture
dc.titleThe Effect of Upright Posture on Endothelial Function in Women and Men
dc.typeElectronic Thesis or Dissertation

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