The role of vitamin d and calcium supplementation in the pathogenesis of type 2 diabetes mellitus

Simple item page
dc.contributor.advisorHamadeh, Mazenen_US
dc.creatorAlabdulkader, Shahd Abudullah
dc.date.accessioned2016-06-23T17:45:58Z
dc.date.available2016-06-23T17:45:58Z
dc.date.copyright2013-12en_US
dc.date.issued2016-06-23
dc.degree.disciplineKinesiology & Health Scienceen_US
dc.degree.levelMaster'sen_US
dc.degree.nameMSc - Master of Scienceen_US
dc.description.abstractMounting evidence suggests a crucial role for vitamin D in the pathogenesis of type 2 diabetes mellitus (T2DM). Our objectives were to examine the correlation between serum calcidiol and diabetes outcomes, and determine whether vitamin 03 and calcium supplementation would attenuate the severity of T2DM. Eleven non-white, post-menopausal women with T2DM (age, 61 ± 11 y) were supplemented for 3 y with either placebo or 1800 IU 03 + 720 mg calcium (CaD)/day. The relative change over 3 y in serum calcidiol significantly inversely correlated with the relative change in body weight, BMI, body fat (%), hip circumference, serum TC/HDL-C and serum PTH, whereas it positively correlated with serum calcium. Retrospective analysis showed differences between the CaD vs. placebo in hip circumference, serum calcidiol, serum PTH and systolic blood pressure. We conclude that modest improvements in vitamin D status may mitigate the decrement in T2DM-related sequelae in non-white, post-menopausal women.en_US
dc.identifier.urihttp://hdl.handle.net/10315/31430
dc.rightsAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.en_US
dc.subject.keywordsDiabetes mellitusen_US
dc.subject.keywordsBMIen_US
dc.subject.keywordsCalciumen_US
dc.subject.keywordsNon-whiteen_US
dc.subject.keywordsPost-menopausalen_US
dc.subject.keywordsWomenen_US
dc.titleThe role of vitamin d and calcium supplementation in the pathogenesis of type 2 diabetes mellitusen_US
dc.typeElectronic Thesis or Dissertationen_US

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Alabdulkader_Shahd_2014_Masters.pdf
Size:
5.45 MB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 2 of 2
No Thumbnail Available
Name:
YorkU_ETDlicense.txt
Size:
3.38 KB
Format:
Plain Text
Description:
Download
No Thumbnail Available
Name:
license.txt
Size:
1.83 KB
Format:
Plain Text
Description:
Download

Collections

Kinesiology & Health Science

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.