Palladium Mediated Synthesis of Substituted Phenols From Acyclic Ketones

dc.contributor.advisor	Orellana Garcia, Josue Arturo
dc.creator	Samadi, Sadaf
dc.date.accessioned	2016-09-20T18:56:47Z
dc.date.available	2016-09-20T18:56:47Z
dc.date.copyright	2016-04-29
dc.date.issued	2016-09-20
dc.date.updated	2016-09-20T18:56:47Z
dc.degree.discipline	Chemistry
dc.degree.level	Master's
dc.degree.name	MSc - Master of Science
dc.description.abstract	The direct functionalization of phenols at the ortho and para position is generally facilitated by the electron-donating nature of the hydroxyl group. Accessing meta substituted phenols, on the other hand, often requires lengthy synthetic sequences. Here, we report a conceptually different method for the one-pot synthesis of substituted phenols by using a pre-functionalization strategy whereby the functional group is installed on the substrate, an acyclic unsaturated ketone, before a cyclization/aromatization reaction. Hence, the functionality is present during the palladium(II) catalyzed reaction. This transformation leads to the formation of various mono-, di-, and trisubstituted phenols with substituents at various positions.
dc.identifier.uri	http://hdl.handle.net/10315/32338
dc.language.iso	en
dc.rights	Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.
dc.subject	Chemistry
dc.subject.keywords	Chemistry
dc.title	Palladium Mediated Synthesis of Substituted Phenols From Acyclic Ketones
dc.type	Electronic Thesis or Dissertation

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