Differences in quality of life across renal replacement therapies: A meta-analytic comparison
| dc.contributor.author | Cameron, Jill | |
| dc.contributor.author | Whiteside, Catherine | |
| dc.contributor.author | Katz, Joel | |
| dc.contributor.author | Devins, Gerald M. | |
| dc.date.accessioned | 2011-05-18T19:20:32Z | |
| dc.date.available | 2011-05-18T19:20:32Z | |
| dc.date.issued | 1999 | |
| dc.description.abstract | A meta-analysis compared emotional distress and psychological well-being across renal replacement therapies (RRTs) and examined whether differences could be explained by: (1) treatment modalities, (2) case mix, or (3) methodologic rigor. Standard meta-analytic procedures were used to evaluate published comparative studies. Successful renal transplantation was associated with: (1) lower distress (effect size, d = −0.43 SD) and greater well-being (d = 0.62 SD) than incenter hemodialysis (CHD) and (2) lower distress (d = −0.29 SD) and greater well-being (d = 0.53 SD) than continuous ambulatory peritoneal dialysis (CAPD). CAPD was characterized by greater well-being (d = 0.18 SD) than CHD and CHD was associated with greater distress (d = 0.16 SD) than home hemodialysis. Although methodologic rigor and case-mix differences did not correlate with the magnitude of psychosocial differences across RRTs, 10 of the 12 comparisons (83%) were threatened by publication bias (ie, that nonsignificant comparisons may have been underrepresented in the published literature). Thus, although significant quality-of-life differences were evident across treatment groups, the types of patients representative of the various RRTs also differed significantly in terms of case-mix variables relevant to psychosocial well-being and emotional distress. Published findings indicating differential quality of life across RRTs may thus be attributable to: (1) valid differences in effective renal replacement, reduced medical complications, and lifestyles afforded by these treatment modalities; (2) case-mix differences in the patient samples selected to represent them in research comparisons; or (3) both of these alternative explanations. | en |
| dc.identifier.citation | American Journal of Kidney Disease, 35(4), 629-637. (2000) | |
| dc.identifier.uri | http://hdl.handle.net/10315/7950 | |
| dc.language.iso | en | en |
| dc.publisher | Elsevier | en |
| dc.rights.article | http://www.sciencedirect.com/science?_ob=MImg&_imagekey=B6W9N-4HGN4PF-9-1&_cdi=6687&_user=866177&_pii=S0272638600700096&_origin=gateway&_coverDate=04%2F30%2F2000&_sk=999649995&view=c&wchp=dGLbVlz-zSkWb&md5=35ed28b4da1b00d34454d9eabff002a1&ie=/sdarticle.pdf | |
| dc.rights.journal | http://www.elsevier.com/wps/find/journaldescription.cws_home/623276/description#description | en |
| dc.rights.publisher | http://www.elsevier.com | en |
| dc.subject | case mix | en |
| dc.subject | psychosocial | en |
| dc.subject | comparative studies | en |
| dc.subject | renal replacement therapy (RRT) | en |
| dc.subject | meta-analysis | en |
| dc.subject | quality of life | en |
| dc.title | Differences in quality of life across renal replacement therapies: A meta-analytic comparison | |
| dc.type | Article | en |