YorkSpace has migrated to a new version of its software. Access our Help Resources to learn how to use the refreshed site. Contact diginit@yorku.ca if you have any questions about the migration.
 

Gender and Sex Differences in Prevalence of Major Depression in Coronary Artery Disease Patients: A Meta-Analysis

Simple item page
dc.contributor.authorShanmugasegaram, Shamila
dc.contributor.authorRussell, Kelly
dc.contributor.authorKovacs, Adrienne
dc.contributor.authorStewart, Donna Eileen
dc.contributor.authorGrace, Sherry L.
dc.date.accessioned2013-06-24T15:09:44Z
dc.date.available2013-06-24T15:09:44Z
dc.date.issued2012-12
dc.description.abstractBackground: Depression is related to increased morbidity and mortality in the general population and among patients with coronary artery disease (CAD). The prevalence of major depression is two-times higher in women than men in the general population, but whether this pattern holds true in the CAD population has not been established. Objective: To test, through quantitative synthesis, whether women with CAD have a greater prevalence of major depression than men. Method: MEDLINE, EMBASE, and PsycINFO electronic databases were searched. Authors of key articles were contacted to identify other relevant publications. The titles and abstracts were screened by the first author and the selected full-text articles were independently screened by the first and second authors based on pre-defined inclusion criteria. Major depression had to be diagnosed through structured clinical interviews during cardiac-related hospitalization or post-CAD hospitalization. Meta-analysis was undertaken using the Review Manager 5 software program. All pooled analyses were based on random-effects models. Results: Eight eligible cohort and cross-sectional studies reporting data for 2072 participants (509 [24.6%] women) were included. Overall, major depression was observed in 95 (18.7%) women and 187 (12.0%) men. In the pooled analysis, prevalence of major depression was significantly greater in women compared to men (odds ratio=1.77, 95% confidence interval=1.21-2.58, p<.01). Heterogeneity was considered low to moderate (I2=36.0%). Conclusion: Consistent with the general population, the prevalence of major depression is two-times greater in women than men with CAD. Women with CAD may warrant greater emphasis in efforts to identify and treat depression.en_US
dc.description.sponsorshipCanadian Institutes of Health Research (CIHR) Frederick Banting and Charles Best Canada Graduate Scholarship -Doctoral Award. CIHR salary award #MSH-80489
dc.identifier.citationMaturitas 73.4 (2012):305-11.
dc.identifier.urihttp://hdl.handle.net/10315/24293
dc.identifier.urihttps://dx.doi.org/10.1016/j.maturitas.2012.09.005
dc.language.isoenen
dc.subjectSex differences
dc.subjectWomen
dc.subjectMen
dc.subjectCoronary artery diseaseDepression
dc.titleGender and Sex Differences in Prevalence of Major Depression in Coronary Artery Disease Patients: A Meta-Analysis
dc.typeArticle

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
SexDiffs Dep_MetaAnalysis_SShan Comp_manuscript_12_clean.doc
Size:
177.5 KB
Format:
Microsoft Word
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.83 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

School of Kinesiology and Health Science

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.