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Effect of Lipotoxicity on ER Stress, Autophagy and Apoptosis in Skeletal Muscle and Regulation by Adiponectin
Obesity is a key factor contributing to the “metabolic syndrome” which increases the risk for type 2 diabetes, cardiovascular disease and liver complications. In obese conditions, lipotoxicity is a serious concern as the ...
The Effects of LCN2 and Iron on Cardiac Remodeling and the Impact on Cardiac Function
Lipocalin-2 (Lcn2; also termed neutrophil gelatinase-associated lipocalin (NGAL)) is a proinflammatory factor which is elevated in obese individuals. It has also been implicated in the pathogenesis of heart failure and as ...