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Mechanisms of High Insulin and High Glucose-Induced Skeletal Muscle Insulin Resistance: Focus on Regulation by Adiponectin
Skeletal muscle insulin resistance is known to play an important role in the pathogenesis of diabetes, however the cellular processes involved are poorly defined. Autophagy, ER stress, the UPR and oxidative stress are being ...
Effect of Lipotoxicity on ER Stress, Autophagy and Apoptosis in Skeletal Muscle and Regulation by Adiponectin
Obesity is a key factor contributing to the “metabolic syndrome” which increases the risk for type 2 diabetes, cardiovascular disease and liver complications. In obese conditions, lipotoxicity is a serious concern as the ...