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Surface and Interfacial Approaches for the Characterization of Biomolecular Interactions and to Optimize Desi-MS Performance
This work involves the surface and interfacial characterization of biomolecular interactions by atomic force microscopy and optimization of desorption electrospray ionization mass spectrometry. In the first part (part I), ...
Ambient Ionization: Surface Analysis of Sexual Assault Evidence and 2-Dimensional Imaging of Whole-Body Zebra Fish (Danio Rerio) Using Desorption Electrospray Ionization
Desorption electrospray ionization (DESI) is an ambient surface analysis technique capable of producing 2D and 3D images. The ionization mechanism utilizes a pneumatically assisted sprayer to deposit a charged solvent onto ...
A Stable Dicationic Salt in Reactive DESI-MS Imaging in Positive Ion Mode to Analyze Biological Samples
A dicationic salt was applied for imaging in reactive desorption electrospray ionization mass spectrometry (DESI-MS) on biological samples. The samples interrogated in this experiment were whole body zebrafish tissues and ...
Investigation of Phospholipids in Ethanol Affected Prenatal Mouse Brain Using DESI-MS Imaging
The prevalence of fetal alcohol spectrum disorder (FASD) is increasing exponentially due to the in-cognizant consumption of alcohol during early pregnancy. This research primarily focuses on monitoring the variation of ...
Characterization, Imaging and Quantitation of Small Molecules by Ambient Ionization Mass Spectrometry
For more than a century mass spectrometry has been a well-known technique in the field of chemical analytics. Its selectivity and sensitivity has made it popular in various fields. From analysis of pure organics, its use ...