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Exploring the Potential of Polyelectrolyte-Aptamer Films For Use in Optical and Electrochemical Sensing
(2016-09-20)
Polyelectrolyte-aptamer films have emerged as versatile and easy-to-fabricate materials for applications ranging from cargo delivery to sensing. The films comprising charged polymers and DNA aptamers exhibit changes in the ...
Silica Sol-Gel Materials as a Catalyst Support for Use in Microwave-Assisted Continuous-Flow Organic Synthesis
(2019-03-05)
The Organ group used microwave irradiation as a means of heating flowed chemical reactions in the development of a microwave-assisted continuous-flow organic synthesis (MACOS) system, to combine the benefits of flow reactions ...
Facile Controlled Preparation of Multifunctional Core-Shell Magnetic Nanoparticles and Their Use in Microfluidic Separation
(2019-03-05)
Continuous microfluidic technology has proven to be a potential competitor with established batch systems for facilitating chemical synthesis and purification, and more amenable to miniaturization, integration, and automation. ...
Nanostructured Mixed Transition Metal Spinel Oxide as Efficient Electrocatalysts
(2016-09-20)
CuxCo3-xO4 films with x values ranging from 0 to 1 have prepared in order to optimize their electrocatalytic properties for the oxygen evolution reaction (OER). Two methods have been used for the preparation of CuxCo3-xO4, ...
Probing Charge Generation in 3D Photonic Poly(3-hexylthiophene)/Titanium Dioxide Nanocomposites for Bulk Heterojunction Solar Cells
(2016-09-20)
Organic photovoltaics (OPVs) are attractive for their inexpensiveness, large-scale fabrication methods, flexibility and semi-transparency. OPVs have lower efficiencies than conventional inorganic semiconductor-based solar ...
Palladium Mediated Synthesis of Substituted Phenols From Acyclic Ketones
(2016-09-20)
The direct functionalization of phenols at the ortho and para position is generally facilitated by the electron-donating nature of the hydroxyl group. Accessing meta substituted phenols, on the other hand, often requires ...
The Cocaine-Binding Aptamer: A Thermodynamic and Structural Overview of Specific and Non-Specific Binding Interactions
(2016-09-20)
Isothermal Titration Calorimetry (ITC) studies were conducted wherein variances in the heat capacity of binding (Cp) among variants of the cocaine-binding aptamer were suggestive of two distinct binding mechanisms. Aptamer ...
Method Development For Concentration Measurements of SVOCs and Analysis of Ambient Samples
(2016-09-20)
Semi-volatile organic compounds (SVOCs) comprise a wide range of toxic pollutants in the atmosphere. Phenols, polycyclic aromatic hydrocarbons (PAHs) and n-alkanes are specific examples of SVOCs that are the focus of this ...
Unravelling the Conformational Dynamics of a-Synuclein's Folding Pathway By Hydrogen-Deuterium Exchange Mass Spectrometry in the Presence of Phospholipid Nanodiscs
(2019-03-05)
Conformational changes of the -synuclein protein during docking into a phospholipid membrane is suspected to play a central role in neuronal cell death during Parkinsons disease. This intrinsically disordered protein obtains ...
Structure-Function Studies of Scaffolding Proteins Involved in the Formation of Neuronal Connections: AIDA1 and CASKIN2
(2017-07-27)
Modular proteins serve assembly platforms and often actively regulate cellular signaling events. An intrinsic diversity of interaction modules, typical for scaffolding proteins, facilitates the organization of numerous ...