Browsing by Subject "C. elegans"
Now showing items 1-5 of 5
-
Hybrid Microfluidic Devices For On-Demand Manipulation and Screening of Neurons and Organs of Small Model Organisms
(2017-07-26)Caenorhabditis elegans and Drosophila melanogaster are widely used model organisms for neurological and cardiac studies due to their simple neuronal and cardiac systems, genome similarity to humans, and ease of maintenance ... -
Investigating the Functional Significance of BRAP-2 in Response to Oxidative Stress in Caenorhabditis Elegans
(2016-11-25)In order to prevent cellular damage caused by reactive oxygen species (ROS), mammals have developed sophisticated defense mechanisms such as the Keap1-Nrf2 oxidative stress response pathway to maintain homeostasis. ... -
Microfluidic Devices for Neural and Behavioral Screening of C.Elegans using Electric Field
(2022-03-03)C. elegans is an invaluable model for studying human diseases, from understanding disease pathology to screening for chemicals toxicity and therapeutic effects. However, technological deficiencies in achieving automated, ... -
Optofluidic Add-on Devices for Light Sheet Fluorescence Microscopy of Caenorhabditis Elegans with Conventional Wide-Field Microscopes
(2022-08-08)This research reports on the development of low-cost and compact optofluidic add-on devices for converting a conventional wide-field microscope to a light sheet fluorescence microscope for immobilization-free, rapid and ... -
The Role of BRAP-2 in Caenorhabditis Elegans DNA Damage Induced Germline Apoptosis Development and Germline Health
(2018-03-01)The DNA damage response protects the genome by executing processes that prevent the disruption of normal cell physiology and the inheritance of mutations. BRCA1 is an essential tumor suppressor gene that facilitates DNA ...