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The Effects of Cardiac Rehabilitation on Mortality and Morbidity in Women: a Meta-Analysis Attempt

dc.contributor.authorLima de Melo Ghisi, Gabriela
dc.contributor.authorChaves, Gabriela Suéllen da Silva
dc.contributor.authorbennett, amanda
dc.contributor.authorLavie, Carl
dc.contributor.authorGrace, Sherry
dc.date.accessioned2021-01-21T19:52:27Z
dc.date.available2021-01-21T19:52:27Z
dc.date.issued2019-01
dc.description.abstractCardiac rehabilitation (CR) reduces mortality and morbidity. However, there have been few women in CR trials, and no meta-analyses. Thirty-one potential trials were identified in recent systematic reviews. All authors were contacted for data by sex as this was rarely reported. Data were only available for 2 trials.en_US
dc.description.abstractBackground: Cardiac rehabilitation (CR) is associated with significant reductions in mortality and morbidity, but few women are included in trials. Therefore, a meta-analysis of the effects of CR in women is warranted. Methods: Randomized controlled trials from recent systematic reviews that included women, attending comprehensive CR, and reporting the outcomes of mortality, morbidity (hospitalization, myocardial infarction, bypass surgery, percutaneous coronary intervention)were considered for inclusion. An updated search of the literature was performed from the end date of the last search, based on the Cochrane strategy. Authors were contacted to request results in women where not reported. Results: Based on 2 recent systematic reviews, 80 trials were identified. Fifty (62.5%) were excluded, most-commonly due to lack of inclusion of women (n=18; 22.5%).One trial was identified through the search update. Of 31 potential trials meeting inclusion criteria, one reported results in women, and many were old and hence data by sex were no longer available. Ultimately, data for women were available in 2. Therefore, it was deemed inappropriate to undertake meta-analysis. Conclusion: This review corroborates the dearth of data on CR in women, despite the fact that it is their leading cause of death. Given the totality of evidence, including reductions in mortality and morbidity in non-randomized studies, and evidence of benefit for other important outcomes such as functional capacity and quality of life, women should continue to be referred to CR.en_US
dc.identifier.citationJournal of Cardiopulmonary Rehabilitation and Prevention: 2019 Jan;39(1):39-42en_US
dc.identifier.issn1932-7501
dc.identifier.urihttps://doi.org/10.1097/HCR.0000000000000351en_US
dc.identifier.urihttp://hdl.handle.net/10315/38060
dc.language.isoenen_US
dc.publisherNational Center for Biotechnology Informationen_US
dc.rightsLWW This is a non-final version of an article published in final form in (Journal of Cardiopulmonary Rehabilitation and Prevention: January 2019 - Volume 39 - Issue 1 - p 39-42). https://cdn-tp2.mozu.com/16833-m1/cms/files/Author-Document.pdf?_mzts=636519775710000000en_US
dc.rightsAttribution-NoDerivatives 4.0 International*
dc.rights.articlehttps://journals.lww.com/jcrjournal/Abstract/2019/01000/The_Effects_of_Cardiac_Rehabilitation_on_Mortality.7.aspxen_US
dc.rights.journalhttps://journals.lww.com/jcrjournal/pages/default.aspxen_US
dc.rights.publisherhttps://www.wolterskluwer.com/en-caen_US
dc.rights.urihttp://creativecommons.org/licenses/by-nd/4.0/*
dc.subjectcardiac rehabilitationen_US
dc.subjectwomenen_US
dc.subjectcoronary heart diseaseen_US
dc.subjectsecondary preventionen_US
dc.titleThe Effects of Cardiac Rehabilitation on Mortality and Morbidity in Women: a Meta-Analysis Attempten_US
dc.typeArticleen_US

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