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A Steroid Driven Peripheral Oscillator in Fat Body Cells of Rhodnius prolixus (Hemiptera)
Circadian clocks are central to physiology. In animals, clocks are distributed in cells and tissues throughout the organism. The specific role of these clocks in the tissues within which they reside as well as the way they ...
Manipulation of Endogenous and Exogenous Sources of Cholesterol and its Effects on Beta Cell Function.
Type 2 diabetes mellitus (T2DM) prevalence continues to increase worldwide. Changes in β-cell function and mechanisms behind the aberrant insulin secretion found in T2DM patients are still poorly understood. Cholesterol ...
Identifying Substrates, Interacting Partners and Cofactors of Pirh2: Characterizing the Pirh2-PKCdelta Interaction
p53 is a central player in the cellular response to stress, allowing cells to cope in the presence of diverse stress signals including DNA damage and oncogene activation. In response to stress, p53 acts as a transcription ...
Characterization of PRD-1 Mutation in Neurospora crassa
In Neurospora crassa, rhythmic conidiation is controlled by several oscillators such as FRQ/WCC and FLO. The frequency (frq) gene and white collar genes (WC-1 and WC-2) are the most important components of the FRQ/WCC ...
Anterior Cingulate Cortex Cells Identify Errors of Attentional Control Prior to Prefrontal Disengagement
The anterior cingulate cortex (ACC) is implicated in the detection of errors and the allocation of correctional adjustments. However, error detection alone is not sufficient to resolve and prevent future mistakes since ...