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Surface and Interfacial Approaches for the Characterization of Biomolecular Interactions and to Optimize Desi-MS Performance 

Ore, Moriam Oluwaseun (2016-11-25)
This work involves the surface and interfacial characterization of biomolecular interactions by atomic force microscopy and optimization of desorption electrospray ionization mass spectrometry. In the first part (part I), ...
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Part One: A Flow Reactor With In-Line Analytics: Design and Implementation Part Two: In-Line Derivatization of Protic Compounds for GC/MS Reaction Monitoring 

Somerville, Kristina Rita (2016-11-25)
The creation of an automated synthetic reaction system with in-line analytics is presented in two parts. First, the design and implementation of a flow reactor system complete with in-line gas chromatography mass spectrometry ...
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Characterization of Structures and Dynamics of Intrinsically Disordered Domain and Proteins Using Time Resolved-Hydrogen Deuterium Exchange Mass Spectrometry 

Zhu, Shaolong (2017-07-27)
Proteins are inherently dynamic. Virtually all of the processes that underlie biological activity, including binding partner recognition, catalysis and allostery among many others, require transient adoption of specific ...
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Novel Kinetic Solution-Based Separation Approaches for Small Molecule Drug Discovery 

Bao, Jiayin (2017-07-27)
The modern pharmaceutical industry has achieved remarkable successes in medicinal chemistry. However, many diseases are incurable due to the difficulty of finding new drugs. De novo drug discovery contains two steps: the ...
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Studies of Protein Function by Liquid Chromatography-Mass Spectrometry 

Declan Williams, Gwillym (2015-01-26)
Complete genomes of many organisms have been recorded using high throughput nucleic acid sequencing; however the intricate functions of the gene products remain largely undiscovered. As the most prominent technology for ...
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A Comparative Study Performed on Two Ambient Ionization Techniques: Desorption Electrospray Ionization Mass Spectrometry (DESI-MS) and Easy Ambient Sonic Spray Ionization Mass Spectrometry (EASI-MS) 

Hamid, Tanam Sanjana (2015-08-28)
Main project of my master’s thesis involved comparison between two sister methods: desorption electrospray ionization mass spectrometry (DESI−MS) and easy ambient ionization mass spectrometry (EASI−MS). These methods are ...
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Evaluating the Utility of an Atmospheric Pressure Chemical Ionization Mass Spectrometer for Detecting Organic Peroxides During Beta-Pinene Ozonolysis Experiments 

Jameer, Amanda Ophelia (2015-08-28)
The intent of this study was to use a positive-ion atmospheric pressure chemical ionization mass spectrometer ((+) APCI-MS/MS) to detect organic peroxide products formed during β-pinene ozonolysis experiments. Detection ...
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Ambient Ionization: Surface Analysis of Sexual Assault Evidence and 2-Dimensional Imaging of Whole-Body Zebra Fish (Danio Rerio) Using Desorption Electrospray Ionization 

Chramow, Alexander (2015-08-28)
Desorption electrospray ionization (DESI) is an ambient surface analysis technique capable of producing 2D and 3D images. The ionization mechanism utilizes a pneumatically assisted sprayer to deposit a charged solvent onto ...
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Mass Spectrometry Methods for Enhanced Characterization of Biological Systems 

Szymkowicz, Lisa Rachel (2019-07-02)
As the pharmaceutical industry moves towards larger protein-based therapeutics over chemically synthesized small molecules, there are increasing demands for parallel advancement in the technologies used for quality control ...
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Chemical and Physical Studies of Secondary Organic Aerosol Formed from Beta-pinene Photooxidation 

Sarrafzadeh, Mehrnaz (2017-07-27)
Atmospheric organic aerosols have a significant impact on climate and human health. However, our understanding of the physical and chemical properties of these aerosols is inadequate, thus their climate and health influences ...
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AuthorBao, Jiayin (1)Chramow, Alexander (1)Declan Williams, Gwillym (1)Hamid, Tanam Sanjana (1)Jameer, Amanda Ophelia (1)Lam, Ka Hang Brian (1)Ore, Moriam Oluwaseun (1)Sarrafzadeh, Mehrnaz (1)Somerville, Kristina Rita (1)Szymkowicz, Lisa Rachel (1)... View MoreSubject
Mass spectrometry (11)
Analytical chemistry (7)Chemistry (6)Atmosphere (2)Biochemistry (2)DESI-MS (2)Hydrogen deuterium exchange mass spectrometry (2)Imaging (2)Ion mobility spectrometry (2)Mass spectrometry imaging (2)... View MoreDate Issued2015 (4)2017 (3)2016 (2)2018 (1)2019 (1)Has File(s)Yes (11)

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.

YorkU LogoContact Us | Send Feedback
link to sitemap