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Bio-Orthogonal Manipulation of Cellular Membranes for Biological Applications 

O'Brien, Paul J. (2018-05-28)
Recent breakthroughs using novel chemistry and nanotechnology methodologies for cellular biology applications have spurred tremendous interest in the development of new technologies to manipulate cell-lines or cellular ...
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Unravelling the Conformational Dynamics of a-Synuclein's Folding Pathway By Hydrogen-Deuterium Exchange Mass Spectrometry in the Presence of Phospholipid Nanodiscs 

Oganesyan, Irina (2019-03-05)
Conformational changes of the -synuclein protein during docking into a phospholipid membrane is suspected to play a central role in neuronal cell death during Parkinsons disease. This intrinsically disordered protein obtains ...
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Part I: Mechanistic Insight in Alkyl-Alkyl and Aryl-Aryl Negishi Cross-Coupling Part II: Large Scale Synthesis of NHC Precursors: 2,6-DI(3-Pentyl) Aniline and 2,6-DI (4-Heptyl) Aniline 

McCann, Lucas Charles (2016-09-20)
Part I: An efficient method for alkyl-alkyl Negishi cross-coupling reaction of unactivated primary alkyl halides with higher-order zincate species (synthesized from dialkylzinc and a non-coordinating halide salt in situ) ...
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Probing Charge Generation in 3D Photonic Poly(3-hexylthiophene)/Titanium Dioxide Nanocomposites for Bulk Heterojunction Solar Cells 

Tulsiram, Nicholas (2016-09-20)
Organic photovoltaics (OPVs) are attractive for their inexpensiveness, large-scale fabrication methods, flexibility and semi-transparency. OPVs have lower efficiencies than conventional inorganic semiconductor-based solar ...
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Palladium Mediated Synthesis of Substituted Phenols From Acyclic Ketones 

Samadi, Sadaf (2016-09-20)
The direct functionalization of phenols at the ortho and para position is generally facilitated by the electron-donating nature of the hydroxyl group. Accessing meta substituted phenols, on the other hand, often requires ...
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Nanostructured Mixed Transition Metal Spinel Oxide as Efficient Electrocatalysts 

Thekkoot, Sreena Raju (2016-09-20)
CuxCo3-xO4 films with x values ranging from 0 to 1 have prepared in order to optimize their electrocatalytic properties for the oxygen evolution reaction (OER). Two methods have been used for the preparation of CuxCo3-xO4, ...
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The Cocaine-Binding Aptamer: A Thermodynamic and Structural Overview of Specific and Non-Specific Binding Interactions 

Reinstein, Oren (2016-09-20)
Isothermal Titration Calorimetry (ITC) studies were conducted wherein variances in the heat capacity of binding (Cp) among variants of the cocaine-binding aptamer were suggestive of two distinct binding mechanisms. Aptamer ...
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Synthesis and Reactivity of Umpolung Reagents Through Transition Metal Catalysis 

Nikolaev, Andrei (2019-03-05)
The cyclopropanol-derived palladium-homoenolates have previously been exploited as a unique class of cross-coupling partners in our group. The major advantage of using cyclopropanols as the cross-coupling partners is the ...
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Characterization of Structures and Dynamics of Intrinsically Disordered Domain and Proteins Using Time Resolved-Hydrogen Deuterium Exchange Mass Spectrometry 

Zhu, Shaolong (2017-07-27)
Proteins are inherently dynamic. Virtually all of the processes that underlie biological activity, including binding partner recognition, catalysis and allostery among many others, require transient adoption of specific ...
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Synthesis, Characterization and Reactivity Study of Bis (Imino)-N-Heterocyclic Carbene Transition Metal Complexes 

Al-Thagfi, Jameel Raddah (2015-08-28)
Three generations of the first 1,3-bis(imino) N-heterocyclic carbene (NHC) ligand precursors were synthesized, isolated and characterized. The synthetic methodologies of the ligand precursors were controlled by the iminic ...
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AuthorAl-Thagfi, Jameel Raddah (2)Nikolaev, Andrei (2)Badaj, Anna Candace (1)Bakhshaei, Baharak (1)Baray, Sabour Ahmad (1)Beloborodov, Stanislav (1)Chen, Xia (1)Chramow, Alexander (1)Consuelo Javiera Perez (1)Dawood, Nusaibah Esmael (1)... View MoreSubject
Chemistry (49)
Analytical chemistry (7)Biochemistry (7)Atmospheric chemistry (6)Mass spectrometry (6)Catalysis (4)NHC (4)Organic chemistry (4)Biology (3)Carbene (3)... View MoreDate Issued2015 (16)2018 (7)2019 (7)2014 (5)2016 (5)2017 (3)2020 (2)2021 (2)2022 (2)Has File(s)Yes (49)

All items in the YorkSpace institutional repository are protected by copyright, with all rights reserved except where explicitly noted.

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