Over the years, various multiparameter methods have been developed to measure the strength of a Lewis acid. However, a major challenge for these measurements lies in the complexity that arises from variables, such as solvent ...

Discovery of new drugs starts with screening a library of drug candidates (ligands) for their ability to bind targets. Such a screening can be conducted by a variety of analytical techniques; however, Capillary Electrophoresis ...

Genipin is a natural compound that forms colours when reacted with primary amines. Curiously, it contains a large amount of uncertainty surrounding its dye structure. It was previously believed that genipin reacts with ...

Pyridines are important frameworks in drug development, valued for their ubiquitous presence in biologically active compounds. As such, we have taken a keen interest in developing mild methods for pyridylic functionalization ...

Enantioselective synthesis using nitrogen containing heterocycles, such as pyridines, is extremely useful in drug discovery. The prevalence of pyridines in the drug market is well-documented and a mild, enantioselective ...