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Contribution of central neuroplasticity to pathological pain: review of clinical and experimental evidence
Peripheral tissue damage or nerve injury often leads to pathological pain processes, such as spontaneous pain, hyperalgesia and allodynia, that persist for years or decades after all possible tissue healing has occurred. ...
Transition from acute to chronic postsurgical pain: risk factors and protective factors
(Expert Reviews, 2009)
Most patients who undergo surgery recover uneventfully and resume their normal daily activities within weeks. Nevertheless, chronic postsurgical pain develops in an alarming proportion of patients. The prevailing approach ...