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The Interplay Between PGC-1 and Autophagy During Metabolic Alterations in Skeletal Muscle
PGC-1α is a transcriptional co-activator well established as a potent regulator of oxidative metabolism in skeletal muscle. This co-activator mediates metabolic adaptation to exercise by orchestrating mitochondrial biogenesis. ...
The Role of PGC-1 alpha in Mediating Exercise-Induced TFEB Expression and Activity in Skeletal Muscle
A healthy mitochondrial pool in skeletal muscle is maintained by the coordinated processes of biogenesis and mitophagy. PGC-1alpha is a key transcriptional co-activator necessary for mitochondrial synthesis, whereas ...