Edgell, HeatherHabib, Karim Hany2021-11-152021-11-152021-082021-11-15http://hdl.handle.net/10315/38746We investigated flow-mediated dilation (FMD) and reactive hyperemia peripheral arterial tonometry (RH-PAT) responses during the supine and 70 head-up tilt postures to assess vascular function in young healthy women and men. During the FMD protocol: 1) FMD increased in both sexes during tilt (P=0.005), 2) women had higher shear stress responses in both postures vs. men (P=0.03), 3) at the time of maximal vasodilation during tilt, both sexes had lower mean arterial pressure responses (MAP; P=0.02) compared to supine. During the RH-PAT protocol: 1) at all timepoints men had greater RH-PAT in comparison to women (P=0.035), 2) both sexes had similar arterial stiffness in both postures (P>0.05), and 3) at the time of maximal vasodilation, both sexes showed similar MAP responses across both postures (P>0.05). We suggest that the increased vasodilatory response as measured by FMD in the tilt posture could be attributed to increasing metabolite production from postural muscles.Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.KinesiologyElectronic Thesis or Dissertation2021-11-15Flow-mediated dilationperipheral arterial tonometrysex differencesvasodilationupright posture