Orellana Garcia, Josue Arturo2016-09-202016-09-202016-04-292016-09-20http://hdl.handle.net/10315/32338The direct functionalization of phenols at the ortho and para position is generally facilitated by the electron-donating nature of the hydroxyl group. Accessing meta substituted phenols, on the other hand, often requires lengthy synthetic sequences. Here, we report a conceptually different method for the one-pot synthesis of substituted phenols by using a pre-functionalization strategy whereby the functional group is installed on the substrate, an acyclic unsaturated ketone, before a cyclization/aromatization reaction. Hence, the functionality is present during the palladium(II) catalyzed reaction. This transformation leads to the formation of various mono-, di-, and trisubstituted phenols with substituents at various positions.enAuthor owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.ChemistryPalladium Mediated Synthesis of Substituted Phenols From Acyclic KetonesElectronic Thesis or Dissertation2016-09-20Chemistry