Sergio, Lauren E.Bumra, Kiran Kaur2025-11-112025-11-112025-07-242025-11-11https://hdl.handle.net/10315/43274Cognitive-motor integration (CMI) refers to the ability to follow rules that guide perception and action. Following a concussion, CMI neural networks are often disrupted, impairing complex movement. We previously identified links between white matter integrity and visuomotor performance in working-age adults with persistent post-concussion symptoms (PPCS). We investigated the impact of sex, age, and CMI processes on visuomotor performance in PPCS. Forty-two adults (47.5 ± 9.87 years; 25 females, 17 males) completed a direct hand-to-target task and an indirect CMI task (plane-change and feedback reversal). Symptom severity, dizziness, cortical volumes and thickness, and resting-state functional connectivity (RSFC) were assessed. Females demonstrated slower CMI task performance, reduced cortical volume (left cuneus and superior frontal), thinner cortex (left precuneus), greater RPQ-3 symptom severity, and lower RSFC across multiple brain networks. Regression showed female sex and older age predicted poorer CMI performance. Findings highlight sex- and age-related neural factors underlying post-concussion motor deficits.Author owns copyright, except where explicitly noted. Please contact the author directly with licensing requests.PsychologyKinesiologyElectronic Thesis or Dissertation2025-11-11ConcussionSex differencesWorking-aged adultsCognitive-motor integrationAgeMRIPersistent post-concussion symptomsVisuomotor performance